I would recommend trying to keep it as clean as possible. If you're routing wires through tubing and you get a jumble of wire or something stuck in there, it's a pain to get out. I would also suggest covering up the edge of the holes through which your wires enter and leave. For example, we put rubber rubber "linings" that cover the edge of the hole in the tube. So when we pull the wires out or push the wires in, they don't get damaged. If you look at the top part of our elevator
in this picture, you can see the wires running out, and the hole covered by the rubber plug.
Running wires and pneumatic tubing through our frame helps us give a clean look to the robot. In addition, it also ensures that they won't get damaged, cut, or caught by other parts of the robot.