[JesseK]

I run VirtualBox in seamless mode with CentOS and occasionally Ubuntu with Windows 8 as the main O/S. I do too much in Windows to give it up entirely (Plug-N-Play hardware, my encrypted USB jump drive, CAD, games, MS Office-required things).

The virtual machines are used so I can develop embedded applications using Linux since I understand the native development tools in Linux far better than Windows PowerShell (awk, sed, grep, find, etc). For my 3D print jobs Slic3r works better in Linux (requires a rebuild to see 3D renders of planned printed parts) but other parts of my process require windows-only apps (Pr0nterface).

VirtualBox seamless mode allows me to have the best of both worlds, most of the time.