[wt200999]

You shouldn't have to worry about it for the robot code since when you 'deploy' the code (at least by default) debugging is disabled. You can see that this is true if you look under the Advanced category for the build specification in the default robot project. In fact I would leave it in for most of your VIs so when you load your code using just the Run button, you can still debug as usual.

Inlining the VI will give you some small performance benefits at the expense of larger compiled code. Just this check box alone will change your benchmark results. It is good for small widgets like the ones in this thread. For the reeentrancy you just have to be careful depending on the VI.