This will be littered with random trivia, I feel.
The New York Hall of Science was designed by Wallace K. Harrison for the 1964-65 New York World's Fair. As such, it's a pretty unique building, and it's not too difficult to find.
It's in Queens, though, not in Manhattan. It's on the former fairgrounds, which is now Flushing Meadow - Corona Park. It's near the Panorama of New York City, which is a consistently updated scale model of New York City's five boroughs. Neat stuff.
Anyway, coming from Connecticut and going straight to the Hall of Science, I think this is the best way to go. . . if there's someone reading from NYC, maybe they know better.
It's pretty easy - I'd just take the Whitestone Bridge to the Grand Central Parkway (East) . . . from there, there ought to be an exit that goes directly to that area, as it's also near Shea Stadium. I'm not sure of the number, but I know it's there
From their website, actually,
From Bronx/Westchester
Cross the Whitestone Bridge, bearing right at the end onto the Whitestone Expressway. Exit onto Grand Central Parkway eastbound. Take exit 10, bearing right to follow the Midtown Tunnel signage. Right on Corona Avenue. Right on 111th Street. Right at 49th Avenue into the New York Hall of Science entrance drive.
From Manhattan, it's the 7 train's 111th street stop. But, well, I guess my point is, it's not in Manhattan
