I didn't want to be random and posted a poll with an opinion right away. Now that there have been a lot of comments, here's my choice.
360: Microsoft does OSes, not VGs. Never have liked their objective to conquer the world of electronic entertainment.
PS3: I lost Sony after E3 2001 with the release of the Cube.
Wii: Wiinner. It got some of the best reviews at E3 2006 with one reporter sayiing that the lines for the Nintendo booth were long all day, and never really shrunk.
Plus, the system looks elegant, seems like it will be fun, plus the virtual console is something to drool over: Finally, a chep solution (hopefully) to rid of illegal emulation (but, if we can't find those Japanese games or extra-special ones in the US, then emu is the only answer, or not play them at all.

)
Other notes:
Super Smash Bros. Brawl looks awesome! Metroid Prime 3 looks and apparently will be better than MP2 (didn't like the dark and light worlds, plus the story line got dull before the half way point of the game.)
Oh yeah, I will be getting a DS Lite in June, that's automatic. A friend already has one from Japan, my sister is getting one too as well, and it is probably the best piece of equipment I have ever seen. Beautiful screen, excellent architecture. Brilliant overall.