[Bryan Herbst]

As Austin said, yes you can.

To drive "Arcade style" (one joystick- X axis controls turning, y controls forward/backward) , simply wire the two axises up to the arcade drive subVI. To get to the axises, simply right click the joystick get subVI's axis output (NOT the button output), and click unbundle by name.

You can also control two non-driving motors in pretty much the same way. First you open the motor, then use the motor set speed subVI. If you want each axis to control a different motor, wire one up to the X, and one to the Y. If you want one axis to control two motors, wire both motors to the single axis.