It depends somewhat on your application and your specific type of caster. For example, 330 uses a lot of pneumatic caster wheels (modified to be driving wheels, that is!)
In general, omni wheel > ball caster > other caster types. But, that does have a few caveats.
First, you hit a major con of casters: You cannot power them. Well, not easily. With an unpowered omni wheel, powering is as simple as adding a sprocket and chain to the rest of your drivetrain, and you gain some forwards traction. Every time you add an unpowered wheel to your drivetrain, you lose normal force on the powered wheels, which loses you frictional forces, which just so happen to provide traction. Long story short, loss of traction. By placing casters, you can lose traction.
A fairly large advantage of omnis/con of casters is that omnis can almost literally drop into a drivetrain with one bolt (the axle) and no frame modifications besides a hole for said axle. (OK, so bearings in the omnis… but close enough.) A caster needs to have multiple mounting points matching the base pattern, which is a little bit more involved and takes some minor planning.
And now we get to the other con listed by the OP. For a pre-assembled, cheap (one he forgot in the pros), smooth-riding, easy-to-mount (well… see previous paragraph) solution, you get: Unpredictable driving motion. You can insert your own scenario where you need predictable driving motion, I’m sure! But with omnis, you know what’s going to happen for sure, whenever you apply power in a given manner.
As a point of comparison:
Omni Wheel Pros:
-Can add power
-Predictable motion
-Can be used as a sensor wheel when unpowered (casters can’t do this as well)
-Drop-in
Omni Wheel Cons:
-Cost
-Fewer sources
-Bumpy ride (depending on type)
Caster Pros:
-Self Contained
-Pre Assembled
-Cheap
-Smooth ride
-Easy to mount with planning
Caster Cons:
-Unpredictable motion
-Extremely difficult to power
-Tougher to mount without planning
-Harder to use as a distance sensor due to said unpredictable motion
FWIW, I’ve seen it said on CD that a peg leg is preferable to a caster wheel.